True Shadow Mage
Playing Aeon, finish the game by using Shadow Bolt to deal the killing blow on each of the guardians.
True Spirit Channeler
Playing Mukai, finish the game by entering every card of every level (not counting extra cards or the shortcut card)
True Rogue Occultist
Playing Rasimov, activate the Immortal ability 6 times and finish the game with full health.
In a single playthrough, upgrade 6 skills from each of the three skill trees, and equip a gold glyph.
Master of my Own Destiny
In a single playthrough, reroll 3 shops, bypass 2 cards, and cast destiny runes once.
Pew! Pew! Pew!
In a single combat, generate 60 reflected projectiles by shooting at a reflective-aura protected creature.