Do Items despawn?

If I drop a bunch of items from my inventory such as swords or if I use an AMIIBO to spawn some stuff and I don't have enough room to pick it all up. Can I leave the stuff in the ground and come back for it at a later time or do items in Breath of the Wild despawn?

Yes items do not stay on the ground forever. If you drop a sword or something from your inventory and come back later on, it will not be there anymore